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New standard of automated cell counter

ADAM-MC2, an automated fluorescence cell counter, performs viability and cell counting measurements using the PI(Propidium Iodide) staining method of combined with advanced image analysis. It only takes 25 seconds to get the result.

KEY FEATURES & BENEFITS
- Less than 25 sec to get results
- Cell therapy quality control
- Cells countable with ADAM-MC2: stem cell / CAR-T cell / CAR-NK cell / Adipose-derived stem cell
- Automated image analysis
- Accurate result, sensitve CMOS detection, and precise automatic stage





Most Accurate Nucleus Cell Counter
ADAM-MC2 is a new standard of automated fluorescence cell counter.
ADAM stands for Advanced Detection and Accurate Measurement.

ADAM-MC2 utilizes sensitive fluorescence dye staining, LED optics and CMOS detection technologies to make the cell analysis more accurate and reliable.
It measures the number of total cells, viable cells, non-viable cells and shows viability results.
Combined with a disposable microfluidic chip, the operation is now extremely simple, easy and cost-effective.










ADVANTAGE #1

Principle of Viability Measurement (PI-Staining Method)

After the samples are stained with fluorescent dye, propidium iodide, which intercalates DNA to stain the nucleus of target cells,
ADAM-MC2 takes fluorescent images automatically.
The obtained images are processed by image analysis software integrated inside the system.




 


ADVANTAGE #2

Counting Aggregated and Irregular-Shaped Cells

ADAM-MC2 provides accurate and reliable results because it counts aggregated and irregular-shaped cells.
In the image above, the images on the right side indicate cells that have been counted by ADAM-MC2.


- Accurate count based on cell size and shape
- Count aggregated cells individually
- Debris is excluded from results

 









ADVANTAGE #3

Cell Therapeutic Applications

ADAM-MC2 can be used as a device to monitor and QC the cell numbers and viability
in the process of manufacturing cells (CAR-T cells, stem cells, etc.) for cell therapy.

In addition, It is possible to use ADAM-MC2 depending on the cell types (Whole blood cell, PBMCs, etc.)
that need to be monitored during the manufacturing of cell therapy products.

 









ADVANTAGE #4

Accuracy & Reproducibility

The graph on the left shows correlation of total cell counting between hemocytometer and ADAM-MC2 using SH-SY5Y cells.
The graph on the right shows that samples with low, medium and high concentration of cells were counted with ADAM-MC2.
The repeatability at each level of cell concentration is high.









ADVANTAGE #5

Comparison of Cell Viability

Comparison of cell viability between ADAM-MC2, flow cytometry, and manual counting
SH-SY5Y, Jurkat, HeLa cells were treated with 100, 300 μM H2O2 for 3 hours,
then analyzed by ADAM-MC2, flow cytometry, and manual counting.







  • Product name / Cat. No.

    ADAM-MC2 / ADAM-MC2

  • Loading volume

    23 µL/test (2channel), 13 µL/test (4channel)

  • Measuring volume

    8.6 µL/test (2channel), 3.4 µL/test (4channel)

  • Measurement range

    5 X 10E4 ~ 4 X 10E6 cells/mL

  • Focus

    Auto-focusing

  • LED

    4W Green LED

  • Weight

    7.0 kg

  • Size (LxWxH)

    277 x 276 x 270 mm

  • Analysis time

    < 50 sec/test (2channel), < 25 sec/test (4channel)

  • LS PRODUCT / ADAM-MC2

    Bead calibration results are out of range.

    1. Please try vortexing of the bead for a minute, or shake the bead bottle.2. Use bead from the new bead bottle.
  • LS PRODUCT / ADAM-MC2

    I see a good number of debris in the screen

    1. Check if there are no scratches outside or no debris inside the r-Slide.2. If you still see debris when using a new control sample, the control sample may be defective. Please contact your control sample manufacturer.